Functional Film Coatings
Tancoat
Tancoat is a range of functional film-coating polymers that control where and how a drug is released, from stomach-protective barriers to colon-targeted delivery. Grades are supplied as powders, granules, organic solutions or aqueous dispersions.
Applications
Enteric coating, moisture & taste masking, sustained-release formulations
01
Enteric coatings
Smooth, stable enteric coatings. Site-specific intestinal delivery can be tuned by combining Tancoat L and Tancoat S grades for a variable release profile.
| Grade | Form | Dissolution profile | Recommended application |
|---|---|---|---|
| Tancoat L-100-55 | Powder | Dissolves at pH 5.5 | Smooth, stable enteric coating with fast dissolution in the upper bowel; drug release in the duodenum |
| Tancoat L-30 D | Aqueous dispersion | Dissolves at pH 5.5 | Drug release in the duodenum |
| Tancoat L-100 | Powder | Dissolves at pH 6.0 | Granulation of drug substances in powder form for controlled release; drug delivery in the jejunum |
| Tancoat L-12.5 | Organic solution | Dissolves at pH 6.0 | Drug delivery in the jejunum |
| Tancoat S-100 | Powder | Dissolves at pH 7.0 | Site-specific intestinal delivery; drug delivery in the colon |
| Tancoat S-12.5 | Organic solution | Dissolves at pH 7.0 | Drug delivery in the colon |
| Tancoat FS-30 D | Aqueous dispersion | Dissolves at pH 7.0 | Drug delivery in the colon |
02
Protective coatings
Soluble in gastric juice up to pH 5.0. Low viscosity, high pigment binding, excellent adhesion and low weight gain.
| Grade | Form |
|---|---|
| Tancoat E-100 | Granules |
| Tancoat E-12.5 | Organic solution |
| Tancoat EPO | Powder |
- Insulating coatings for moisture barrier
- Taste masking
- Odor masking
- Light protection
03
Sustained-release coatings
Insoluble, pH-independent swelling polymers. Customized release profiles are achieved by combining RL and RS grades in different ratios.
| Grade | Form | Permeability |
|---|---|---|
| Tancoat RL 100 | Granules | High |
| Tancoat RL 12.5 | Organic solution | High |
| Tancoat RLPO | Powder | High |
| Tancoat RS 100 | Granules | Low |
| Tancoat RS 12.5 | Organic solution | Low |
| Tancoat RSPO | Powder | Low |
| Tancoat NE 30 D | Aqueous dispersion | pH-independent swelling |
- Improved patient compliance
- Cost-effective processing
- Sustained-release formulations